WebCK-666 是一种细胞渗透性的与肌动蛋白相关的蛋白质 Arp2/3 复合物的抑制剂 ( IC50 =12 μM),它结合 Arp2/3 复合物,稳定复合物的非活性状态,阻止 Arp2 和 Arp3 亚单位移动进入激活的丝状构象。 MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务 我们将采用定制合成服务的方式为您快速提供所需产品和技术服务 CK-666 … WebCK-666 suppresses the enhanced memory phenotype of msi-1 (lf) by inhibiting the Arp2/3 complex activity. In addition, inhibition of Arp2/3, involved in actin filament branching and neuronal morphogenesis, in the lateral amygdala (LA) with the specific inhibitor CK-666 during fear conditioning impaired long-term fear memory in rats. [2]
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WebCK 666, Actin polymerization inhibitor Description Potent inhibitor of actin polymerization Biological description Potent inhibitor of actin polymerization. Inhibits the Arp2/3 (IC 50 = 17 μM), SpArp2/3 (IC 50 = 5 μM) and HsArp2/3 complexes (IC 50 = 4 μM) by preventing a shift into an active conformation. Purity > 99% CAS Number 442633-00-3 WebApr 25, 2013 · CK-666 at 200 μM eliminated the Arp2-Arp3 crosslink formed in the absence of activating factors, and reduced the amount of the cross linked band formed in the presence GST-VCA or GST-VCA and actin (Fig. 5G,H). These data demonstrate that CK-666 blocks formation of the short pitch conformation, explaining how it inhibits nucleation … fnf mod super mario 3d world
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WebPreparing Stock Solutions for CK 666. The following data is based on the product molecular weight 296.34. Batch specific molecular weights may vary from batch to batch due to the … WebSep 5, 2010 · CHERRY CK-606 はバーアンテナの設計が良い感じです。 下530Khz 上1634Khzで トラッキングしましたが 中間での感度が弓なりのよいラインになります。 追記 ラジオキット等は、 こちらのカテゴリー です。 追記 2011,01,03 TR換装、R定数変更など手を加えると ①KIT-9 ②6TR-STD≒CK-606 の順によく聞こえます。 追記 2011.01.11 … http://bbradio.sakura.ne.jp/board6/board6.html fnf mods wiki applecore