WebCryptotanshinone interferes with chondrocyte apoptosis in osteoarthritis by inhibiting the expression of miR‑574‑5p. PMID 33878859; DOI 10.3892/mmr.2024.12063; Molecular medicine reports 2024 06; 23 (6): Name matches: bcl-2 cryptotanshinone. Evidence from. Web目的观察丹参二萜醌类活性成分对胰腺癌的抑制效应,探讨其诱导胰腺癌凋亡的作用机制。方法胰腺癌细胞AsPC-1、BxPC-3用含10%gibco胎牛血清的RPMI1640培养液培养,按隐丹参酮组(30μM)、丹参新酮组(15μM)、去氢丹参新酮组(15μM)分别加药处理。Cell …
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WebBackground and purpose: Cryptotanshinone (CTS) is a major bioactive diterpenoid isolated from Danshen, an eminent medicinal herb that is used to treat cardiovascular disorders in … WebMar 2, 2024 · Cryptotanshinone (CPT), as a major component of Salvia miltiorrhiza Bunge (Danshen), displays many pharmacological activities including anti-inflammatory effects. However, the exact cellular and molecular mechanisms of the anti-inflammatory activities of CPT remain to be elucidated. The present study was aimed to clarify its mechanisms on …
WebSep 2, 2024 · 2.1. Cryptotanshinone Delayed Progressive Paralysis of AD C. elegans and Decreased the Ratio of Exogenous Serotonin-Induced Acute Paralysis . Aβ-induced neurotoxicity is one of the most important features of Alzheimer’s disease [].To further evaluate the effect of CTS treatment on Aβ-induced pathology, a temperature-sensitive C. … WebMar 19, 2024 · Cancer is a common malignant disease worldwide with an increasing mortality in recent years. Salvia miltiorrhiza, a well-known traditional Chinese medicine, has been used for the treatment of cardiovascular and cerebrovascular diseases for thousands of years. The liposoluble tanshinones in S. miltiorrhiza are important bioactive …
WebCryptotanshinone (CT), one major lipophilic component isolated from Salvia miltiorrhiza Bunge, has shown to possess chemopreventive properties against various types of … Web目的:观察丹参酮对冠心病心绞痛(心血淤阻型)患者的疗效并做初步评价,并对其机制做初步探究。方法:选取符合纳入标准的冠心病稳定型心绞痛(心血瘀阻型)患者60人,随机分为两组,治疗组30人,对照组30人。入院时常规检查,记录患者心电图改变程度及所需生化指标,记录患者临床症状。两 ...
Web別名: クリプトタンシノン. タンシノンC. ( R )-1,2,6,7,8,9-ヘキサヒドロ-1,6,6-トリメチルフェナントロ [1,2- b ]フラン-10,11-ジオン. Tanshinone C. ( R )-1,2,6,7,8,9-Hexahydro-1,6,6 …
Web目的:观察丹参、泽泻对非酒精性脂肪肝大鼠肝脏纤溶系统的影响.方法:采用喂饲高脂饲料复制非酒精性脂肪肝模型,将60只Wistar大鼠随机分为6组,正常组、模型组、丹参组,泽泻组,丹泽组和东宝肝泰对照组,正常喂养1周后,除正常组和模型组灌胃给予蒸馏水外,其余各给药组分别灌胃给予丹参水煎剂、泽泻 ... highlights deloitteWebMar 2, 2024 · Cryptotanshinone (CPT), as a major component of Salvia miltiorrhiza Bunge (Danshen), displays many pharmacological activities including anti-inflammatory effects. … highlights der normandieWebCryptotanshinone is a STAT3 inhibitor with IC50 of 4.6 μM in a cell-free assay, strongly inhibits phosphorylation of STAT3 Tyr705, with a small effect on STAT3 Ser727, but none against STAT1 nor STAT5. Cryptotanshinone … small plastic pitcherWebCryptotanshinone can also inhibit alcoholic liver disease by blocking hepatic cell death and fatty acid synthesis (Yin et al., 2009). Salvianolic acid B, isolated from S. miltiorrhiza , … small plastic pegboardWeb它不仅影响AR功能,也能显著抑制AR转录活性和AR靶基因在mRNA和蛋白质水平表达,同时还阻断AR和赖氨酸一特异性脱甲基酶一1LSD1)之间的相互作用,抑制AR的靶基因启动子,增加了组蛋白H3赖氨酸9 (H3K9)的单甲基和二甲基化。. 丹参有效成分. 隐丹参酮 (cryptotanshinone ... small plastic plant holdersWebDec 30, 2024 · Cryptotanshinone (CT), a diterpene that is isolated from Salvia miltiorrhiza Bunge, exhibits anti-cancer, anti-oxidative, anti-fibrosis, and anti-inflammatory properties. Here, we examined whether CT administration possess a hepatoprotective effect on chronic ethanol-induced liver injury. We established a chronic alcohol feeding mouse model ... small plastic pipe fittingsWebAug 13, 2024 · Hepatocellular carcinoma (HCC) is a fatal and dominant form of liver cancer that currently has no effective treatment or positive prognosis. In this study, we explored the antitumor effects of cryptotanshinone (CPT) against HCC and the molecular mechanisms underlying these effects using a systems pharmacology and experimental validation … small plastic pitcher with spout