WebSystemic sclerosis (SSc) is a rare connective tissue disease characterized by vascular remodeling, fibroblast activation and extra-cellular matrix production in excess and autoimmunity. WebJun 2, 2024 · Other autoimmune diseases such as rheumatoid arthritis, Sjogren’s syndrome, systemic sclerosis, multiple sclerosis, and inflammatory bowel disease have also been associated with IRF5 ...
IRF5 gene: MedlinePlus Genetics
WebSystemic Lupus Erythematosus; Macrophage; View all Topics. Add to Mendeley. Set alert. About this page. ... the efficacy of interferon therapy for multiple sclerosis is associated … WebJun 15, 2024 · Systemic sclerosis (SSc) is a complex disease, in which an interaction of genetic and environmental factors plays an important role in its development and … san diego overnight fishing
Frontiers Potential T Cell-Intrinsic Regulatory Roles for IRF5 via ...
WebC-reactive protein (CRP) is an acute-phase protein in humans that is produced in high quantities by the liver upon infection and under inflammatory conditions. Although CRP is commonly used as a marker of inflammation, CRP can also directly contribute to inflammation by eliciting pro-inflammatory cytokine production by immune cells. Since … WebA potential disease susceptibility gene for SSc is IFN regulatory factor 5 (IRF5), whose SNP is associated with milder clinical manifestations; however, the underlying mechanisms of this association remain elusive. In this study we examined IRF5-deficient (Irf5 -/-) mice in the bleomycin-treated SSc murine model. WebApr 11, 2024 · Swim training partially reverses changes in LA metabolism in ALS murine skeletal muscle by influencing the glycolytic enzyme and malate dehydrogenase activities, thus improving skeletal muscle mass by adjusting the energy demands. In addition, a step toward precision medicine in ALS has been performed by the study of Renzini A. et al. [ 5 ]. san diego old town trolley tour map